Zepbound

Recommended Dose Escalation Schedule

• The recommended starting dosage of ZEPBOUND for all indications is 2.5 mg injected subcutaneously once weekly for 4 weeks.
• The 2.5 mg dosage is for treatment initiation and is not approved as a maintenance dosage.
• Follow the dosage escalation below for all indications to reduce the risk of gastrointestinal adverse reactions.
• After 4 weeks, increase the dosage to 5 mg injected subcutaneously once weekly. The dosage may be increased in 2.5 mg increments, after at least 4 weeks on the current dose.
• Consider treatment response and tolerability when selecting the maintenance dosage. If patients do not tolerate a maintenance dosage, consider a lower maintenance dosage.